In this section, you can access to the latest technical information related to the FUTURE project topic.

The combination of sesamol and clofibric acid moieties leads to a novel potent hypolipidemic agent with antioxidant, anti-inflammatory and hepatoprotective activity

Oxidative stress and inflammation have been considered the main factors in the liver injury of clofibrate (CF). To obtain a novel antihyperlipidemic agent with antioxidant, anti-inflammation and hepatoprotection, the combination of sesamol and clofibric acid moieties was performed and achieved sesamol-clofibrate (CF-Sesamol). CF-Sesamol showed significant hypolipidemia effects in hyperlipidemia mice induced by Triton WR 1339, reducing TG by 38.8% (P?

» Author: Yundong Xie, Jiping Liu, Yongheng Shi, Bin Wang, Xiaoping Wang, Wei Wang, Meng Sun, Xinya Xu, Haihui Jiang, Min Guo, Yiyi He, Cuicui Ren, Lifei Cheng

» Publication Date: 15/07/2021

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