In this section, you can access to the latest technical information related to the FUTURE project topic.

Design and synthesis of acrylate and acrylamide substituted pyrimidinediones as potential PPO herbicides

PPO herbicides emerge to be widely use in the agricultural field and a focus of research to many scientists due to its environmentally-friendly properties. In lieu with this, this study presents acrylate and acrylamide substituted pyrimidinediones as PPO herbicide candidates. Most synthesized compounds exhibits herbicidal activities against both monocot and dicot weeds, especially, compound 5a which showed non-selective superior activity against the commercialized, Saflufenacil. Compound 5a was further tested for residual effect and showed promising results as shorter period is needed to cultivate the next crops. The synthesized acrylate and acrylamide substituted pyrimidinediones, especially, 5a could potentially be utilized in the development of commercial protoporphyrinogen oxidase inhibitors with further tests and studies.

» Author: Won Hyung Lee, Young Bin Kwon, Jung Hee Kim, Kye Hwan Lee, Shizuka Mei Bautista Maezono, Jong-Soo Choi, Young-Bae Seu

» Publication Date: 01/02/2021

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