In this section, you can access to the latest technical information related to the FUTURE project topic.

<i>Vibrio cholerae</i> strains with inactivated <i>cqs</i>S gene overproduce autoinducer-2 which enhances resuscitation of dormant environmental <i>V</i>. <i>cholerae</i>

AbstractBackground

Toxigenic Vibrio cholerae resides in aquatic reservoirs of cholera-endemic areas mostly in a dormant form known as conditionally viable environmental cells (CVEC) in which the bacteria remain embedded in an exopolysaccharide matrix, and fail to grow in routine bacteriological culture. The CVEC can be resuscitated by supplementing culture media with either of two autoinducers CAI-1 and AI-2, which are signal molecules controlling quorum sensing, a regulatory network of bacterial gene expression dependent on cell density. This study investigated possible existence of variant strains that overproduce AIs, sufficient to resuscitate CVEC in environmental waters.

» Author: Iftekhar Bin Naser,  M. Mozammel Hoque,  Shah Nayeem Faruque,  M. Kamruzzaman,  Shinji Yamasaki,  Shah M. Faruque

» Reference: https://doi.org/10.1371/journal.pone.0223226

» Publication Date: 01/10/2019

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